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EcR mutant midgut comparison

ABSTRACT: Comparisons between EcR mutant midgut and a reference control sample from mixed-stage normal midgut Keywords = Drosophila, ecdysone, network, genomic, microarray, organogenesis, EcR, midgut, central nervous system, salivary gland, epidermis, imaginal disc, development

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Tong-Ruei Li

PROVIDER: E-GEOD-540 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Tissue-specific gene expression and ecdysone-regulated genomic networks in Drosophila.

Li Tong-Ruei TR White Kevin P KP

Developmental cell 20030701 1

During insect metamorphosis, each tissue displays a unique physiological and morphological response to the steroid hormone 20-hydroxyecdysone (ecdysone). We assayed gene expression in five tissues during metamorphosis onset. Larval-specific tissues display major changes in genome-wide expression profiles, whereas tissues that survive into adulthood display few changes. In one larval tissue, the salivary gland, we used a computational approach to identify a regulatory motif and a cognate transcri ...[more]

PMID: 12852852

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