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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of yeast treated with rapamycin, time series

ABSTRACT:

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: unknown unknown

PROVIDER: E-MAXD-4 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Growth control of the eukaryote cell: a systems biology study in yeast.

Castrillo Juan I JI Zeef Leo A LA Hoyle David C DC Zhang Nianshu N Hayes Andrew A Gardner David Cj DC Cornell Michael J MJ Petty June J Hakes Luke L Wardleworth Leanne L Rash Bharat B Brown Marie M Dunn Warwick B WB Broadhurst David D O'Donoghue Kerry K Hester Svenja S SS Dunkley Tom Pj TP Hart Sarah R SR Swainston Neil N Li Peter P Gaskell Simon J SJ Paton Norman W NW Lilley Kathryn S KS Kell Douglas B DB Oliver Stephen G SG

Journal of biology 20070101 2

<h4>Background</h4>Cell growth underlies many key cellular and developmental processes, yet a limited number of studies have been carried out on cell-growth regulation. Comprehensive studies at the transcriptional, proteomic and metabolic levels under defined controlled conditions are currently lacking.<h4>Results</h4>Metabolic control analysis is being exploited in a systems biology study of the eukaryotic cell. Using chemostat culture, we have measured the impact of changes in flux (growth rat ...[more]

PMID: 17439666

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