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Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of rat mixed-tissue RNA samples over 8.5 months to monitor processing drift

ABSTRACT: Process drift at one site was monitored by assaying the rat Mixed Tissue RNA Reference Material (see E-TABM-16) multiple times a week for 8.5 months.

ORGANISM(S): Rattus norvegicus

SUBMITTER: P Scott Pine

PROVIDER: E-MEXP-1565 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Use of diagnostic accuracy as a metric for evaluating laboratory proficiency with microarray assays using mixed-tissue RNA reference samples.

Pine P S PS Boedigheimer M M Rosenzweig B A BA Turpaz Y Y He Y D YD Delenstarr G G Ganter B B Jarnagin K K Jones W D WD Reid L H LH Thompson K L KL

Pharmacogenomics 20081101 11

Effective use of microarray technology in clinical and regulatory settings is contingent on the adoption of standard methods for assessing performance. The MicroArray Quality Control project evaluated the repeatability and comparability of microarray data on the major commercial platforms and laid the groundwork for the application of microarray technology to regulatory assessments. However, methods for assessing performance that are commonly applied to diagnostic assays used in laboratory medic ...[more]

PMID: 19018728

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2010-03-30 | E-TABM-16 | biostudies-arrayexpress

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