Dataset Information
Transcription profiling of Francisella tularensis LVS wild type and hfq mutant strains grown on defined liquid medium (Chamberlains medium)
Ontology highlight
ABSTRACT:
ORGANISM(S): Francisella tularensis
SUBMITTER: Karin Meibom
PROVIDER: E-MEXP-1892 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Hfq, a novel pleiotropic regulator of virulence-associated genes in Francisella tularensis.
Infection and immunity 20090217 5
Francisella tularensis is a highly infectious pathogen that infects animals and humans, causing tularemia. The ability to replicate within macrophages is central for virulence and relies on expression of genes located in the Francisella pathogenicity island (FPI), as well as expression of other genes. Regulation of FPI-encoded virulence gene expression in F. tularensis involves at least four regulatory proteins and is not fully understood. Here we studied the RNA-binding protein Hfq in F. tulare ...[more]
