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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of Francisella tularensis LVS carrying plasmid pFNLTP6-gro or pFNLTP-gro-0851 (expressing rpoH) grown to mid exponential phase

ABSTRACT: F. tularensis LVS carrying plasmid pFNLTP6-gro or pFNLTP-gro-0851 (expressing rpoH) were grown to mid exponential phase in Schaedler + vitamin K3 medium and RNA isolated.

ORGANISM(S): Francisella tularensis

SUBMITTER: Karin Meibom

PROVIDER: E-MEXP-2048 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Pivotal role of the Francisella tularensis heat-shock sigma factor RpoH.

Grall Nathalie N Livny Jonathan J Waldor Matthew M Barel Monique M Charbit Alain A Meibom Karin L KL

Microbiology (Reading, England) 20090514 Pt 8

Francisella tularensis is a highly infectious pathogen that infects animals and humans to cause the disease tularemia. The primary targets of this bacterium are macrophages, in which it replicates in the cytoplasm after escaping the initial phagosomal compartment. The ability to replicate within macrophages relies on the tightly regulated expression of a series of genes. One of the most commonly used means of coordinating the regulation of multiple genes in bacteria consists of the association o ...[more]

PMID: 19443547

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