Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Leo Zeef
PROVIDER: E-MEXP-2084 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Boros Joanna J Donaldson Ian J IJ O'Donnell Amanda A Odrowaz Zaneta A ZA Zeef Leo L Lupien Mathieu M Meyer Clifford A CA Liu X Shirley XS Brown Myles M Sharrocks Andrew D AD
Genome research 20090817 11
Transcription factors play an important role in orchestrating the activation of specific networks of genes through targeting their proximal promoter and distal enhancer regions. However, it is unclear how the specificity of downstream responses is maintained by individual members of transcription-factor families and, in most cases, what their target repertoire is. We have used ChIP-chip analysis to identify the target genes of the ETS-domain transcription factor ELK1. Two distinct modes of ELK1 ...[more]