Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Imprinting of the Polycomb Group Gene MEDEA Serves as a Ploidy Sensor in Arabidopsis

ABSTRACT: Comparison of fis2 and jas mutants and tetraploid x diploid crosses.

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Lars Hennig

PROVIDER: E-MEXP-2316 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Publications

Imprinting of the polycomb group gene MEDEA serves as a ploidy sensor in Arabidopsis.

Erilova Aleksandra A Brownfield Lynette L Exner Vivien V Rosa Marisa M Twell David D Mittelsten Scheid Ortrun O Hennig Lars L Köhler Claudia C

PLoS genetics 20090925 9

Balanced maternal and paternal genome contributions are a requirement for successful seed development. Unbalanced contributions often cause seed abortion, a phenomenon that has been termed "triploid block." Misregulation of imprinted regulatory genes has been proposed to be the underlying cause for abnormalities in growth and structure of the endosperm in seeds with deviating parental contributions. We identified a mutant forming unreduced pollen that enabled us to investigate direct effects of ...[more]

PMID: 19779546

Similar Datasets

Imprinting of the polycomb group gene MEDEA serves as a ploidy sensor in Arabidopsis.

Project description:Balanced maternal and paternal genome contributions are a requirement for successful seed development. Unbalanced contributions often cause seed abortion, a phenomenon that has been termed "triploid block." Misregulation of imprinted regulatory genes has been proposed to be the underlying cause for abnormalities in growth and structure of the endosperm in seeds with deviating parental contributions. We identified a mutant forming unreduced pollen that enabled us to investigate direct effects of unbalanced parental genome contributions on seed development and to reveal the underlying molecular mechanism of dosage sensitivity. We provide evidence that parent-of-origin-specific expression of the Polycomb group (PcG) gene MEDEA is causally responsible for seed developmental aberrations in Arabidopsis seeds with increased paternal genome contributions. We propose that imprinted expression of PcG genes is an evolutionary conserved mechanism to balance parental genome contributions in embryo nourishing tissues.

| S-EPMC2738949 | biostudies-literature

Transcription profiling of wild type and transgenic msi1-cs plants

Project description:Wild type and transgenic msi1-cs plants were grown and gene expression was compared at two time points at the age of 23 days.

2009-01-10 | E-MEXP-1829 | biostudies-arrayexpress

Transcription profiling of human hepatoma-derived Huh7 cells carrying the Hepatitus C virus clone 21-5, cells in which the virus has been eliminated and parental cells

Project description:Hepatitis C virus (HCV) RNA synthesis and protein expression affect cell homeostasis by modulation of gene expression. The impact of HCV replication on global cell transcription has not been fully evaluated. Thus, we analysed the expression profiles of different clones of human hepatoma-derived Huh7 cells carrying a self-replicating HCV RNA which express all viral proteins (HCV replicon system). First, we compared the expression profile of HCV replicon clone 21-5 with both the Huh-7 parental cells and the 21-5 cured (21-5c) cells. In these latter, the HCV RNA has been eliminated by IFN-? treatment. To confirm data, we also analyzed microarray results from both the 21-5 and two other HCV replicon clones, 22-6 and 21-7, compared to the Huh-7 cells. The study was carried out by using the Applied Biosystems (AB) Human Genome Survey Microarray v1.0 which provides 31,700 probes that correspond to 27,868 human genes. A total of 15 hybridization were performed, allowing to compare transcription profiles among the following groups of cell lines: - HCV replicon clone: 21-5 (4 hybs) - cured HCV replicon clone: 21-5c (4 hybs) - parental cell line: Huh-7 (4 hybs) - other HCV replicon clones: 21-7 (2 hybs); 22-6 (1 hyb)

2008-06-27 | E-MEXP-1686 | biostudies-arrayexpress

Transcription profiling by array of human sarcomas developed in the field of irradiation after radiotherapy.

Project description:Transcriptome signature of the ionizing radiation effect in sarcomas developed in the field of irradiation after radiotherapy

2011-03-31 | E-MEXP-2687 | biostudies-arrayexpress

Transcription profiling by array of human oocytes to investigate the association between meiotic aneuploidy and altered oocyte gene expression

Project description:This study combined a comprehensive cytogenetic investigation of oocytes with a detailed assessment of their transcriptome. The 1st polar body was removed from all oocytes and aneuploidy assessed using comparative genomic hybridization. mRNA transcript data was produced with the use of microarrays for 7 of the corresponding oocytes (3 normal and 4 aneuploid). The results obtained for normal and aneuploid oocytes were compared and 327 genes were found to display statistically significant differences in transcript levels.

2010-06-05 | E-MEXP-2745 | biostudies-arrayexpress

Albrecht_SCO3

Project description:4 days old seedlings grown on MS without sucrose under continuous light of sco3-1 and Col have been used to extract RNA. Microarray analysis has been performed with three independent biological replicates

2010-10-30 | E-MEXP-2927 | biostudies-arrayexpress

Kolsto-B. cereus Comparison of WT and BC4707 mutant during growth in logarithmic phase

Project description:Comparison of B. cereus ATCC14579 wild type and its isogenic BC4707 mutant under growth in logarithmic phase

2012-01-31 | E-MEXP-3537 | biostudies-arrayexpress

MiRNA expression in airway epithelial wound repair_Szczepankiewicz

Project description:Analysis of miRNA expression at different time points of epithelial wound repair of 16HBE14o- cells after mechanical damage of cell monolayer.

2013-10-02 | E-MEXP-3986 | biostudies-arrayexpress

Transcription profiling of chicken jejuna in a time series after orally infection with Salmonella

Project description:RNA was extracted form chicken jejuna at 0.33,1, 2, 4, 8, 12 and 21 days post-infection, in orally infected (1.10^5 Salmonella ) and control chickens. NOTE: Normalization is performed separately! on control and infected chickens, because the objective was to investigate differences in development.

2010-03-01 | E-MEXP-2042 | biostudies-arrayexpress

Transcription profiling of yeast sum1 delta strain at three time points after the start of meiosis

Project description:Expression profiling of sum1 delta strain at three time points after the start of meiosis

2010-04-20 | E-MEXP-2154 | biostudies-arrayexpress