Unknown,Transcriptomics,Genomics,Proteomics

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Interactome of Human Embryo Implantation: Identification of Gene Expression Pathways, Regulation, and Integrated Regulatory Networks.


ABSTRACT: Possible interactions between endometrium and implanting embryo in humans

ORGANISM(S): Homo sapiens

SUBMITTER: Juri Reimand 

PROVIDER: E-MEXP-3111 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Research resource: interactome of human embryo implantation: identification of gene expression pathways, regulation, and integrated regulatory networks.

Altmäe Signe S   Reimand Jüri J   Hovatta Outi O   Zhang Pu P   Kere Juha J   Laisk Triin T   Saare Merli M   Peters Maire M   Vilo Jaak J   Stavreus-Evers Anneli A   Salumets Andres A  

Molecular endocrinology (Baltimore, Md.) 20111110 1


A prerequisite for successful embryo implantation is adequate preparation of receptive endometrium and the establishment and maintenance of a viable embryo. The success of implantation further relies upon a two-way dialogue between the embryo and uterus. However, molecular bases of these preimplantation and implantation processes in humans are not well known. We performed genome expression analyses of human embryos (n = 128) and human endometria (n = 8). We integrated these data with protein-pro  ...[more]

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