Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Lapatinib and retinoic acid combination treatment of SKBR3 breast cancer cells


ABSTRACT: SKBR3 cells, which bear both an HER2 and a RARA gene amplification, were treated for 12 or 48 hours with 100 nM retinoic acid, 100 nM lapatinib or the combination.The two drugs synergize and induce massive apoptosis. The aim is to find the molecular mechanism(s) of this synergism. Gene expression profiling was performed using Agilent two-color 4X44K arrays. Original processed data are available in the archive: http://www.ebi.ac.uk/arrayexpress/files/E-MEXP-3192/E-MEXP-3192.additional.zip

ORGANISM(S): Homo sapiens

SUBMITTER: Maddalena Fratelli 

PROVIDER: E-MEXP-3192 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2008-08-04 | E-MEXP-1681 | biostudies-arrayexpress
2009-05-19 | E-MEXP-1900 | biostudies-arrayexpress
2011-03-30 | E-MEXP-2655 | biostudies-arrayexpress
2010-02-12 | E-MEXP-2523 | biostudies-arrayexpress
2012-10-31 | E-MEXP-3448 | biostudies-arrayexpress
2010-12-15 | E-MEXP-2830 | biostudies-arrayexpress
2010-03-13 | E-MEXP-2418 | biostudies-arrayexpress
2011-01-01 | E-MEXP-2878 | biostudies-arrayexpress
2011-03-30 | E-MEXP-2670 | biostudies-arrayexpress
2012-04-15 | E-MEXP-3185 | biostudies-arrayexpress