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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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CGH analyses of human induced pluripotent stem cells

ABSTRACT: Human induced pluripotent stem cells (hIPSCs) represent a unique opportunity for regenerative medicine since they offer the prospect of generating unlimited quantities of cells for autologous transplantation as a novel treatment for a broad range of disorders. However, the use of hIPSCs in the context of genetically inherited human disease will require correction of disease-causing mutations in a manner that is fully compatible with clinical applications. Genomic instability induced by reprogramming or genetic modification would be a main issue for the safe use of these cells. We analyzed primary hIPSC lines and genetically modified derivatives by array-based comparative genomic hybridization.

ORGANISM(S): Homo sapiens

SUBMITTER: Kosuke Yusa

PROVIDER: E-MEXP-3316 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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