Integration of transcriptome, proteome and phoshpoproteome data elucidates the genetic control of molecular networks
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ABSTRACT: 150 cultures of 112 Saccharomyces cerevisiae strains (BYxRM cross) were grown in full medium and harvested in log phase. RNA was isolated and quantified via RNAseq. The reads were subsequently mapped against strain-specific genomes. The same cultures were also characterized on the proteomic and phosphoproteomic layers. This data was used to investigate the effects of natural variation on molecular traits in budding yeast. Candidate causal genes (GPA1, STE20) were investigated through allele replacement strains.
INSTRUMENT(S): Illumina HiSeq 4000, Illumina HiSeq 2000
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Jan Grossbach
PROVIDER: E-MTAB-8146 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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