Ontology highlight
ABSTRACT:
SUBMITTER: Wang L
PROVIDER: S-EPMC2735584 | biostudies-literature | 2008 Dec
REPOSITORIES: biostudies-literature
Wang Lin L Buchanan Stacey S Meyerhoff Mark E ME
Analytical chemistry 20081201 24
A very simple and inexpensive method to detect oversulfated chondroitin sulfate (OSCS) or other high-charge density polyanionic structures as contaminants in heparin products using potentiometric polyanion sensors is described. In the potentiometric measurement, a greater change in the phase boundary equilibrium potential of polymeric membranes formulated with tridodecylmethylammonium (TDMA) anion exchange sites is observed for the contaminated heparin than for the untainted heparin due to the h ...[more]