Ontology highlight
ABSTRACT:
SUBMITTER: Pagano B
PROVIDER: S-EPMC2738904 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Pagano Bruno B Mattia Carlo Andrea CA Giancola Concetta C
International journal of molecular sciences 20090702 7
G-quadruplexes are higher-order nucleic acids structures formed by G-rich sequences that are stabilized by tetrads of hydrogen-bonded guanine bases. Recently, there has been growing interest in the study of G-quadruplexes because of their possible involvement in many biological processes. Isothermal titration calorimetry (ITC) has been proven to be a useful tool to study the energetic aspects of G-quadruplex interactions. Particularly, ITC has been applied many times to determine the thermodynam ...[more]