Ontology highlight
ABSTRACT:
SUBMITTER: Wan Q
PROVIDER: S-EPMC3094545 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Wan Qun Q Ahmad Md Faiz MF Fairman James J Gorzelle Bonnie B de la Fuente María M Dealwis Chris C Maguire Michael E ME
Structure (London, England : 1993) 20110501 5
The ZntB Zn(2+) efflux system is important for maintenance of Zn(2+) homeostasis in Enterobacteria. We report crystal structures of ZntB cytoplasmic domains from Salmonella enterica serovar Typhimurium (StZntB) in dimeric and physiologically relevant homopentameric forms at 2.3 Å and 3.1 Å resolutions, respectively. The funnel-like structure is similar to that of the homologous Thermotoga maritima CorA Mg(2+) channel and a Vibrio parahaemolyticus ZntB (VpZntB) soluble domain structure. However, ...[more]