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Pd(II)-catalyzed enantioselective C-H olefination of diphenylacetic acids.


ABSTRACT: Pd(II)-catalyzed enantioselective C-H olefination of diphenylacetic acid substrates has been achieved through the use of monoprotected chiral amino acid ligands. The absolute configuration of the resulting olefinated products is consistent with that of a proposed C-H insertion intermediate.

SUBMITTER: Shi BF 

PROVIDER: S-EPMC2806936 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature

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Pd(II)-catalyzed enantioselective C-H olefination of diphenylacetic acids.

Shi Bing-Feng BF   Zhang Yang-Hui YH   Lam Jonathan K JK   Wang Dong-Hui DH   Yu Jin-Quan JQ  

Journal of the American Chemical Society 20100101 2


Pd(II)-catalyzed enantioselective C-H olefination of diphenylacetic acid substrates has been achieved through the use of monoprotected chiral amino acid ligands. The absolute configuration of the resulting olefinated products is consistent with that of a proposed C-H insertion intermediate. ...[more]

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