Ontology highlight
ABSTRACT:
SUBMITTER: Paglia G
PROVIDER: S-EPMC2830312 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Paglia Giuseppe G Ifa Demian R DR Wu Chunping C Corso Gaetano G Cooks R Graham RG
Analytical chemistry 20100301 5
Molecular imaging of separate but still incompletely resolved spots on high-performance thin-layer chromatography (HPTLC) plates is used for the direct analysis of porcine brain lipids by desorption electrospray ionization mass spectrometry (DESI-MS). Eight class-specific spots were imaged in the negative ion mode and shown to contain more than fifty lipids. A low lateral resolution of 400 x 400 microm allowed simple, rapid, and incomplete separation to be combined with DESI imaging for the iden ...[more]