Ontology highlight
ABSTRACT:
SUBMITTER: COGENT Study
PROVIDER: S-EPMC2836775 | biostudies-literature | 2008 Dec
REPOSITORIES: biostudies-literature
Nature genetics 20081116 12
Genome-wide association (GWA) studies have identified multiple loci at which common variants modestly influence the risk of developing colorectal cancer (CRC). To enhance power to identify additional loci with similar effect sizes, we conducted a meta-analysis of two GWA studies, comprising 13,315 individuals genotyped for 38,710 common tagging SNPs. We undertook replication testing in up to eight independent case-control series comprising 27,418 subjects. We identified four previously unreporte ...[more]