Ontology highlight
ABSTRACT:
SUBMITTER: Sugimoto M
PROVIDER: S-EPMC2972219 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Sugimoto Mayumi M Sasaki Shinji S Watanabe Toshio T Nishimura Shota S Ideta Atsushi A Yamazaki Maya M Matsuda Keiko K Yuzaki Michisuke M Sakimura Kenji K Aoyagi Yoshito Y Sugimoto Yoshikazu Y
PloS one 20101103 11
Ionotropic glutamate receptors mediate most excitatory neurotransmission in the central nervous system by opening ion channels upon the binding of glutamate. Despite the essential roles of glutamate in the control of reproduction and anterior pituitary hormone secretion, there is a limited understanding of how glutamate receptors control ovulation. Here we reveal the function of the ionotropic glutamate receptor AMPA-1 (GRIA1) in ovulation. Based on a genome-wide association study in Bos taurus, ...[more]