Ontology highlight
ABSTRACT:
SUBMITTER: Lillington JE
PROVIDER: S-EPMC3021122 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Lillington James E D JE Lovett Janet E JE Johnson Steven S Roversi Pietro P Timmel Christiane R CR Lea Susan M SM
Journal of molecular biology 20101112 2
Shigella flexneri Spa15 is a chaperone of the type 3 secretion system, which binds a number of effectors to ensure their stabilization prior to secretion. One of these effectors is IpgB1, a mimic of the human Ras-like Rho guanosine triphosphatase RhoG. In this study, Spa15 alone and in complex with IpgB1 has been studied by double electron electron resonance, an experiment that gives distance information showing the spacial separation of attached spin labels. This distance is explained by determ ...[more]