Ontology highlight
ABSTRACT:
SUBMITTER: Meleady P
PROVIDER: S-EPMC3170212 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Meleady Paula P Doolan Padraig P Henry Michael M Barron Niall N Keenan Joanne J O'Sullivan Finbar F Clarke Colin C Gammell Patrick P Melville Mark W MW Leonard Mark M Clynes Martin M
BMC biotechnology 20110724
<h4>Background</h4>The ability of mammalian cell lines to sustain cell specific productivity (Qp) over the full duration of bioprocess culture is a highly desirable phenotype, but the molecular basis for sustainable productivity has not been previously investigated in detail. In order to identify proteins that may be associated with a sustained productivity phenotype, we have conducted a proteomic profiling analysis of two matched pairs of monoclonal antibody-producing Chinese hamster ovary (CHO ...[more]