Ontology highlight
ABSTRACT:
SUBMITTER: Tello-Aburto R
PROVIDER: S-EPMC3352666 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Organic letters 20120404 8
The first asymmetric total synthesis and determination of the absolute configuration for the neuroactive marine macrolide palmyrolide A is described. The highlight of the synthesis is macrocyclization via trans-enamide formation catalyzed by copper(I) iodide and cesium carbonate. Comparison with the authentic spectral data confirms the synthesis of (+)-ent-palmyrolide A. ...[more]