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N-[4-(2-Propyn-1-yl-oxy)phen-yl]acetamide.

ABSTRACT: The title compound, C(11)H(11)NO(2), was synthesized by chemoselective N-acetyl-ation of 4-amino-phenol followed by reaction with propargyl bromide in the presence of K(2)CO(3). the acetamide and propyn-1-yloxy substituents form dihedral angles of 18.31?(6) and 7.01?(10)°, respectively, with the benzene ring. In the crystal, mol-ecules are linked by N-H?O hydrogen bonds into chains along [010]. C-H?O and C-H?? inter-actions also occur.

SUBMITTER: Belay YH

PROVIDER: S-EPMC3515179 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature

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N-[4-(2-Propyn-1-yl-oxy)phen-yl]acetamide.

Belay Yonas H YH Kinfe Henok H HH Muller Alfred A

Acta crystallographica. Section E, Structure reports online 20121006 Pt 11

The title compound, C(11)H(11)NO(2), was synthesized by chemoselective N-acetyl-ation of 4-amino-phenol followed by reaction with propargyl bromide in the presence of K(2)CO(3). the acetamide and propyn-1-yloxy substituents form dihedral angles of 18.31 (6) and 7.01 (10)°, respectively, with the benzene ring. In the crystal, mol-ecules are linked by N-H⋯O hydrogen bonds into chains along [010]. C-H⋯O and C-H⋯π inter-actions also occur. ...[more]

PMID: 23284406

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