Ontology highlight
ABSTRACT:
SUBMITTER: Lowe DM
PROVIDER: S-EPMC3608034 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Lowe David M DM Bangani Nonzwakazi N Mehta Meera R MR Lang Dirk M DM Rossi Adriano G AG Wilkinson Katalin A KA Wilkinson Robert J RJ Martineau Adrian R AR
Tuberculosis (Edinburgh, Scotland) 20130117 2
Despite abundant evidence that neutrophils arrive early at sites of mycobacterial disease and phagocytose organisms, techniques to assay phagocytosis or killing of mycobacteria by these cells are lacking. Existing assays for measuring the antimycobacterial activity of human leukocytes require cell lysis which introduces new bioactive substances and may be incomplete. They are also time-consuming and carry multiple risks of inaccuracy due to serial dilution and organism clumping. Flow cytometric ...[more]