Ontology highlight
ABSTRACT:
SUBMITTER: Han D
PROVIDER: S-EPMC3609929 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Han Da D Zhu Guizhi G Wu Cuichen C Zhu Zhi Z Chen Tao T Zhang Xiaobing X Tan Weihong W
ACS nano 20130222 3
Photodynamic therapy is one of the most promising and noninvasive methods for clinical treatment of different malignant diseases. Here, we present a novel strategy of designing an aptamer-based DNA nanocircuit capable of selective recognition of cancer cells, controllable activation of photosensitizers, and amplification of photodynamic therapeutic effect. The aptamers can selectively recognize target cancer cells and bind to the specific proteins on cell membranes. Then the overhanging catalyst ...[more]