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General synthetic approach to functionalized dihydrooxepines.

ABSTRACT: A three-step sequence to access functionalized 4,5-dihydrooxepines from cyclohexenones has been developed. This approach features a regioselective Baeyer-Villiger oxidation and subsequent functionalization via the corresponding enol phosphate intermediate.

SUBMITTER: Nicolaou KC

PROVIDER: S-EPMC3653422 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature

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General synthetic approach to functionalized dihydrooxepines.

Nicolaou K C KC Yu Ruocheng R Shi Lei L Cai Quan Q Lu Min M Heretsch Philipp P

Organic letters 20130404 8

A three-step sequence to access functionalized 4,5-dihydrooxepines from cyclohexenones has been developed. This approach features a regioselective Baeyer-Villiger oxidation and subsequent functionalization via the corresponding enol phosphate intermediate. ...[more]

PMID: 23550898

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