Ontology highlight
ABSTRACT:
SUBMITTER: Cornax I
PROVIDER: S-EPMC3709627 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Cornax Ingrid I Diel Diego G DG Rue Cary A CA Estevez Carlos C Yu Qingzhong Q Miller Patti J PJ Afonso Claudio L CL
The Journal of general virology 20130220 Pt 6
The fusion (F) and haemagglutinin-neuraminidase (HN) proteins of Newcastle disease virus (NDV) are multifunctional proteins that play critical roles during infection. Here, we assessed the ability of NDV to replicate in macrophages and investigated the contribution of the F and HN proteins to NDV infection/replication in these cells. Results of our study revealed that, while presenting similar replication kinetics in a fibroblast cell line (DF1) or in primary non-adherent splenocytes, the NDV st ...[more]