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New terpenes from the Egyptian soft coral Sarcophyton ehrenbergi.

ABSTRACT: Chemical investigations of the Egyptian soft coral Sarcophyton ehrenbergi have led to the isolation of compounds 1-3 as well as the previously reported marine cembranoid diterpene sarcophine (4). Structures were elucidated by comprehensive NMR and HRMS experimentation. Isolated compounds were in vitro assayed for cytotoxic activity against human hepatocarcinoma (HepG2) and breast adenocarcinoma (MCF-7) cell lines.

SUBMITTER: Elkhateeb A

PROVIDER: S-EPMC4012453 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature

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New terpenes from the Egyptian soft coral Sarcophyton ehrenbergi.

Elkhateeb Ahmed A El-Beih Ahmed A AA Gamal-Eldeen Amira M AM Alhammady Montaser A MA Ohta Shinji S Paré Paul W PW Hegazy Mohamed-Elamir F ME

Marine drugs 20140402 4

Chemical investigations of the Egyptian soft coral Sarcophyton ehrenbergi have led to the isolation of compounds 1-3 as well as the previously reported marine cembranoid diterpene sarcophine (4). Structures were elucidated by comprehensive NMR and HRMS experimentation. Isolated compounds were in vitro assayed for cytotoxic activity against human hepatocarcinoma (HepG2) and breast adenocarcinoma (MCF-7) cell lines. ...[more]

PMID: 24699113

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