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Isoprenoids from the Soft Coral Sarcophyton glaucum.

ABSTRACT: Five new isoprenoids, 3,4,8,16-tetra-epi-lobocrasol (1), 1,15?-epoxy-deoxysarcophine (2), 3,4-dihydro-4?,7?,8?-trihydroxy-?²-sarcophine (3), ent-sarcophyolide E (4), and 16-deacetyl- halicrasterol B (5) and ten known compounds 6?15, were characterized from the marine soft coral Sarcophyton glaucum, collected off Taitung coastline. Their structures were defined by analyzing spectra data, especially 2D NMR and electronic circular dichroism (ECD). The structure of the known compound lobocrasol (7) was revised. Cytotoxicity potential of the isolated compounds was reported, too.

SUBMITTER: Chao CH

PROVIDER: S-EPMC5532644 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature

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Isoprenoids from the Soft Coral Sarcophyton glaucum.

Chao Chih-Hua CH Li Wen-Liang WL Huang Chiung-Yao CY Ahmed Atallah F AF Dai Chang-Feng CF Wu Yang-Chang YC Lu Mei-Chin MC Liaw Chih-Chuang CC Sheu Jyh-Horng JH

Marine drugs 20170627 7

Five new isoprenoids, 3,4,8,16-tetra-epi-lobocrasol (1), 1,15β-epoxy-deoxysarcophine (2), 3,4-dihydro-4α,7β,8α-trihydroxy-Δ²-sarcophine (3), ent-sarcophyolide E (4), and 16-deacetyl- halicrasterol B (5) and ten known compounds 6‒15, were characterized from the marine soft coral Sarcophyton glaucum, collected off Taitung coastline. Their structures were defined by analyzing spectra data, especially 2D NMR and electronic circular dichroism (ECD). The struc ...[more]

PMID: 28653983

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