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Arylation and heteroarylation of thienylsulfonamides with organotrifluoroborates.


ABSTRACT: A mild, practical protocol has been developed for the Suzuki cross-coupling of unprotected thienylsulfonamides from air- and bench-stable organotrifluoroborates in the absence of a protecting group on the sulfonamide nitrogen. The developed synthetic method can be applied to the preparation of various arylated and heteroarylated thienylsulfonamides under conditions that are tolerant of a broad range of functional groups.

SUBMITTER: Noreen M 

PROVIDER: S-EPMC4120984 | biostudies-literature |

REPOSITORIES: biostudies-literature

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