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Synthesis, Characterization, and Antifungal Studies of Cr(III) Complex of Norfloxacin and Bipiridyl Ligand.

ABSTRACT: A novel slightly distorted octahedral complex of Cr(III) of norfloxacin (Nor) with the formula [Cr(III)(Nor)(Bipy)Cl2]Cl·2CH3OH has been synthesized hydrothermally in the presence of a N-containing heterocyclic compound 2,2'-bipyridyl (Bipy). The complex was characterized with FT-IR, elemental analysis, UV-visible spectroscopy, and X-ray crystallography. Spectral studies suggest that the Nor acts as a deprotonated bidentate ligand. Thermal studies were also carried out. The synthesised complex was screened against four fungi Pythium aphanidermatum (PA), Sclerotinia rolfsii (SR), Rhizoctonia solani (RS), and Rhizoctonia bataticola (RB).

SUBMITTER: Debnath A

PROVIDER: S-EPMC4168151 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Synthesis, Characterization, and Antifungal Studies of Cr(III) Complex of Norfloxacin and Bipiridyl Ligand.

Debnath Anamika A Hussain Firasat F Masram Dhanraj T DT

Bioinorganic chemistry and applications 20140903

A novel slightly distorted octahedral complex of Cr(III) of norfloxacin (Nor) with the formula [Cr(III)(Nor)(Bipy)Cl2]Cl·2CH3OH has been synthesized hydrothermally in the presence of a N-containing heterocyclic compound 2,2'-bipyridyl (Bipy). The complex was characterized with FT-IR, elemental analysis, UV-visible spectroscopy, and X-ray crystallography. Spectral studies suggest that the Nor acts as a deprotonated bidentate ligand. Thermal studies were also carried out. The synthesised complex w ...[more]

PMID: 25276111

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