The ensembl regulatory build.
Ontology highlight
ABSTRACT:
SUBMITTER: Zerbino DR
PROVIDER: S-EPMC4407537 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Publications
The ensembl regulatory build.
Zerbino Daniel R DR Wilder Steven P SP Johnson Nathan N Juettemann Thomas T Flicek Paul R PR
Genome biology 20150324
Most genomic variants associated with phenotypic traits or disease do not fall within gene coding regions, but in regulatory regions, rendering their interpretation difficult. We collected public data on epigenetic marks and transcription factor binding in human cell types and used it to construct an intuitive summary of regulatory regions in the human genome. We verified it against independent assays for sensitivity. The Ensembl Regulatory Build will be progressively enriched when more data is ...[more]
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