Ontology highlight
ABSTRACT:
SUBMITTER: Jung A
PROVIDER: S-EPMC4478964 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Jung Arong A Garcia Jessica E JE Kim Eunha E Yoon Bong-June BJ Baker Bradley J BJ
Neurophotonics 20150305 2
Several genetically encoded fluorescent sensors of voltage were created by systematically truncating the length of the linker sequence between the voltage-sensing domain and the position of the fluorescent protein, Super Ecliptic A227D. In addition to varying the length, the amino acid composition at the fusion site for the fluorescent protein was modified. Both linker length and amino acid composition affected the size and voltage sensitivity of the optical signal. The truncation mutants reveal ...[more]