Reversible DNA micro-patterning using the fluorous effect.
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ABSTRACT:
SUBMITTER: Flynn GE
PROVIDER: S-EPMC5358500 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Publications
Reversible DNA micro-patterning using the fluorous effect.
Flynn Gabriella E GE Withers Jamie M JM Macias Gerard G Sperling Justin R JR Henry Sarah L SL Cooper Jonathan M JM Burley Glenn A GA Clark Alasdair W AW
Chemical communications (Cambridge, England) 20170301 21
We describe a new method for the immobilisation of DNA into defined patterns with sub-micron resolution, using the fluorous effect. The method is fully reversible via a simple solvent wash, allowing the patterning, regeneration and re-patterning of surfaces with no degradation in binding efficiency following multiple removal/attachment cycles of different DNA sequences. ...[more]
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