Ontology highlight
ABSTRACT:
SUBMITTER: Guo YA
PROVIDER: S-EPMC5391976 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Guo Yi-An YA Lee Wonchul W Krische Michael J MJ
Chemistry (Weinheim an der Bergstrasse, Germany) 20170127 11
Oxetanes bearing all-carbon quaternary stereocenters are readily prepared through the iridium-catalyzed anti-diastereo- and enantioselective C-C coupling of primary alcohols and isoprene oxide. Based on this methodology, an oxetane containing analogue of haloperidol was prepared. A related azetidine formation is also described. ...[more]