Ontology highlight
ABSTRACT:
SUBMITTER: Cheng G
PROVIDER: S-EPMC5553125 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20170609 28
Palladium(II)-catalyzed meta-C-H arylation and alkylation of benzylsulfonamide using 2-carbomethoxynorbornene (NBE-CO<sub>2</sub> Me) as a transient mediator are realized by using a newly developed electron-deficient directing group and isoquinoline as a ligand. This protocol features broad substrate scope and excellent functional-group tolerance. The meta-substituted benyzlsulfonamides can be readily transformed into sodium sulfonates, sulfonate esters, and sulfonamides, as well as styrenes by ...[more]