Synthesis and nitric oxide releasing properties of novel fluoro S-nitrosothiols.
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ABSTRACT:
SUBMITTER: Zhou Y
PROVIDER: S-EPMC6380185 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Publications
Synthesis and nitric oxide releasing properties of novel fluoro S-nitrosothiols.
Zhou Yang Y Tan Jinyi J Dai Yuping Y Yu Yanmin Y Zhang Qi Q Meyerhoff Mark E ME
Chemical communications (Cambridge, England) 20190101 3
A series of new fluoro S-nitrosothiols is reported as potential nitric oxide (NO) donors. A three-step synthesis and the NO releasing kinetic profiles of these species are presented. The stoichiometric release of NO, with the clean formation of corresponding disulfides, confirms that these new species can facilitate their application as NO donors for various applications including creating novel antimicrobial and thromboresistant fluoropolymer-based medical devices. ...[more]
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