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New Furanocembranoids from Briareum violaceum.

ABSTRACT: Three new furanocembranoids-briaviodiol F (1) and briaviotriols A (2) and B (3)-along with a known analogue, briaviodiol A (4), were obtained from a cultured-type octocoral Briareum violaceum. The structures of cembranoids 1?3 were elucidated by using spectroscopic methods. In vitro study demonstrated that compounds 2 and 4 exerted inhibition effects on inducible nitric oxide synthase (iNOS) release from RAW 264.7, a macrophage cell line that originated from a mouse monocyte macrophage, stimulated with lipopolysaccharides.

SUBMITTER: Huang PC

PROVIDER: S-EPMC6520705 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature

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New Furanocembranoids from Briareum violaceum.

Huang Pin-Chang PC Lin Wen-Sou WS Peng Bo-Rong BR Chang Yu-Chia YC Fang Lee-Shing LS Li Guo-Qiang GQ Hwang Tsong-Long TL Wen Zhi-Hong ZH Sung Ping-Jyun PJ

Marine drugs 20190405 4

Three new furanocembranoids-briaviodiol F (1) and briaviotriols A (2) and B (3)-along with a known analogue, briaviodiol A (4), were obtained from a cultured-type octocoral Briareum violaceum. The structures of cembranoids 1⁻3 were elucidated by using spectroscopic methods. In vitro study demonstrated that compounds 2 and 4 exerted inhibition effects on inducible nitric oxide synthase (iNOS) release from RAW 264.7, a macrophage cell ...[more]

PMID: 30959843

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