Crystal structure of (E)-N-cyclo-hexyl-2-(2-hy-droxy-3-methyl-benzyl-idene)hydrazine-1-carbo-thio-amide.

ABSTRACT: The asymmetric unit of the title compound, C₁₅H₂₁N₃OS, comprises of two crystallographically independent mol-ecules (A and B). Each mol-ecule consists of a cyclo-hexane ring and a 2-hy-droxy-3-methyl-benzyl-idene ring bridged by a hydrazinecarbo-thio-amine unit. Both mol-ecules exhibit an E configuration with respect to the azomethine C=N bond. There is an intra-molecular O-H?N hydrogen bond in each mol-ecule forming an S(6) ring motif. The cyclo-hexane ring in each mol-ecule has a chair conformation. The benzene ring is inclined to the mean plane of the cyclo-hexane ring by 47.75?(9)° in mol-ecule A and 66.99?(9)° in mol-ecule B. The mean plane of the cyclo-hexane ring is inclined to the mean plane of the thio-urea moiety [N-C(=S)-N] by 55.69?(9) and 58.50?(8)° in mol-ecules A and B, respectively. In the crystal, the A and B mol-ecules are linked by N-H?S hydrogen bonds, forming 'dimers'. The A mol-ecules are further linked by a C-H?? inter-action, hence linking the A-B units to form ribbons propagating along the b-axis direction. The conformation of a number of related cyclo-hexa-nehydrazinecarbo-thio-amides are compared to that of the title compound.

SUBMITTER: Arafath MA 

PROVIDER: S-EPMC6659332 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature