Dataset Information
One-step templated synthesis of chiral organometallic salicyloxazoline complexes.
Ontology highlight
ABSTRACT: Background
The general approach to the synthesis of metal complexes begins with ligand synthesis, followed by ligand reaction with metal salts to afford organometallic complexes. Our research group first reported a one-pot multicomponent synthesis of chiral oxazolinyl-zinc complexes, in the presence of a large amount of ZnCl2 (0.4-2.6 equiv.), with the yields of some products reaching 90%.Results
Our prior strategy was extended to use copper, cobalt, nickel, manganese, palladium or platinum salts as the third component. The one-step method used 1.0 equivalent of a metal salt, such as M(OAc)2·nH2O or MCl2·nH2O (M: Cu, Co, Ni, Pd or Pt, n?=?1, 2 or 4), as a reagent to generate chiral salicyloxazoline complexes 1-8 in the reaction of 2-cyanophenol with different d- and l-amino alcohols.Conclusion
Complexes 1-8 were obtained using a one-pot method with a sequential strategy. The reaction outcome was demonstrated for three-component reactions between metal salts, amino alcohols and 2-hydroxybenzonitrile to afford organometallic complexes in good yields (65-95%).
SUBMITTER: Luo M
PROVIDER: S-EPMC6661745 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Publications
One-step templated synthesis of chiral organometallic salicyloxazoline complexes.
BMC chemistry 20190404 1
<h4>Background</h4>The general approach to the synthesis of metal complexes begins with ligand synthesis, followed by ligand reaction with metal salts to afford organometallic complexes. Our research group first reported a one-pot multicomponent synthesis of chiral oxazolinyl-zinc complexes, in the presence of a large amount of ZnCl<sub>2</sub> (0.4-2.6 equiv.), with the yields of some products reaching 90%.<h4>Results</h4>Our prior strategy was extended to use copper, cobalt, nickel, manganese, ...[more]