Ontology highlight
ABSTRACT:
SUBMITTER: Atorino ES
PROVIDER: S-EPMC7021698 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Atorino Enrico S ES Hata Shoji S Funaya Charlotta C Neuner Annett A Schiebel Elmar E
Nature communications 20200214 1
Centrosomes are essential organelles with functions in microtubule organization that duplicate once per cell cycle. The first step of centrosome duplication is the daughter centriole formation followed by the pericentriolar material recruitment to this centriole. This maturation step was termed centriole-to-centrosome conversion. It was proposed that CEP295-dependent recruitment of pericentriolar proteins drives centriole conversion. Here we show, based on the analysis of proteins that promote c ...[more]