Ontology highlight
ABSTRACT:
SUBMITTER: Sofronov OO
PROVIDER: S-EPMC7212517 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Sofronov Oleksandr O OO Giubertoni Giulia G Pérez de Alba Ortíz Alberto A Ensing Bernd B Bakker Huib J HJ
The journal of physical chemistry letters 20200421 9
The carboxyl (COOH) side chain groups of amino acids, such as aspartic acid, play an important role in biochemical processes, including enzymatic proton transport. In many theoretical studies, it was found that the (bio)chemical reactivity of the carboxyl group strongly depends on the conformation of this group. Interestingly, up to now there has been no experimental investigation of the geometry and the stability of different COOH conformers under biorelevant conditions. Here, we investigate th ...[more]