Unknown

Dataset Information

0

Synthesis of New Highly Functionalized 1H-Indole-2-carbonitriles via Cross-Coupling Reactions.


ABSTRACT: An approach for the preparation of polysubstituted indole-2-carbonitriles through a cross-coupling reaction of compounds 1-(but-2-ynyl)-1H-indole-2-carbonitriles and 1-benzyl-3-iodo-1H-indole-2-carbonitriles is described. The reactivity of indole derivatives with iodine at position 3 was studied using cross-coupling reactions. The Sonogashira, Suzuki-Miyaura, Stille and Heck cross-couplings afforded a variety of di-, tri- and tetra-substituted indole-2-carbonitriles.

SUBMITTER: Hrizi A 

PROVIDER: S-EPMC8434198 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC4882187 | biostudies-literature
| S-EPMC3678543 | biostudies-literature
| S-EPMC5722243 | biostudies-literature
| S-EPMC3127456 | biostudies-literature
| S-EPMC6682060 | biostudies-literature