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Cyclohexanone and Phenolic Acid Derivatives from Endophytic Fungus Diaporthe foeniculina.

ABSTRACT: Chemical investigation of an endophytic fungus Diaporthe foeniculina SCBG-15, led to the isolation of eight new cyclohexanone derivatives, foeniculins A-H (1-8) and three new phenolic acid derivatives, foeniculins I-K (9-11). Their structures were extensively established on the basis of ¹H and ¹³C NMR spectra together with COSY, HSQC, HMBC, and NOESY experiments. The absolute configurations were confirmed by quantum chemical ECD calculations and single-crystal X-ray diffractions. Moreover, the in vitro cytotoxic and antibacterial activities of isolated compounds 1-11 were also evaluated.

SUBMITTER: Lu X

PROVIDER: S-EPMC8440800 | biostudies-literature |

REPOSITORIES: biostudies-literature

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