Dataset Information
Cryo-electron tomography of FIB-milled Caulobacter crescentus expressing PopZ with IDR-156 and pentavalent OD
Ontology highlight
ABSTRACT:
SUBMITTER: Vinson Lam
PROVIDER: EMPIAR-10689 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems.
Nature communications 20220926 1
Intracellular phase separation is emerging as a universal principle for organizing biochemical reactions in time and space. It remains incompletely resolved how biological function is encoded in these assemblies and whether this depends on their material state. The conserved intrinsically disordered protein PopZ forms condensates at the poles of the bacterium Caulobacter crescentus, which in turn orchestrate cell-cycle regulating signaling cascades. Here we show that the material properties of t ...[more]