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2-[(1S,3S)-3-Acetyl-2,2-dimethyl-cyclo-butyl]-N-(m-tol-yl)acetamide.

ABSTRACT: The title compound, C(17)H(23)NO(2), contains two chiral centres and was synthesized from 2-(3-acetyl-2,2-dimethyl-cyclo-butyl)acetic acid and m-toluidine. The cyclobutane ring is not flat but flexed as though folded from the dimethyl-substituted C atom to the unsubstituted C atom, with a dihedral angle of 25.9°. The crystal structure is stabilized by N-H?O and C-H?O hydrogen-bonding inter-actions.

SUBMITTER: Yin YB

PROVIDER: S-EPMC2915342 | biostudies-other | 2007 Dec

REPOSITORIES: biostudies-other

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2-[(1S,3S)-3-Acetyl-2,2-dimethyl-cyclo-butyl]-N-(m-tol-yl)acetamide.

Yin Yan-Bai YB Song Zhan-Qian ZQ Wang Zong-De ZD Shang Shi-Bin SB

Acta crystallographica. Section E, Structure reports online 20071218 Pt 1

The title compound, C(17)H(23)NO(2), contains two chiral centres and was synthesized from 2-(3-acetyl-2,2-dimethyl-cyclo-butyl)acetic acid and m-toluidine. The cyclobutane ring is not flat but flexed as though folded from the dimethyl-substituted C atom to the unsubstituted C atom, with a dihedral angle of 25.9°. The crystal structure is stabilized by N-H⋯O and C-H⋯O hydrogen-bonding inter-actions. ...[more]

PMID: 21200856

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