Dataset Information
Palladium(ii)-catalyzed γ-selective hydroarylation of alkenyl carbonyl compounds with arylboronic acids.
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ABSTRACT:
SUBMITTER: Matsuura R
PROVIDER: S-EPMC6247822 | biostudies-other | 2018 Nov
REPOSITORIES: biostudies-other
Publications
Palladium(ii)-catalyzed γ-selective hydroarylation of alkenyl carbonyl compounds with arylboronic acids.
Chemical science 20180906 44
A catalytic γ-selective <i>syn</i>-hydroarylation of alkenyl carbonyl compounds using arylboronic acids has been developed using a substrate directivity approach with a palladium(ii) catalyst. This method tolerates a wide range of functionalized (hetero)arylboronic acids and a variety of substitution patterns on the alkene. Preliminary mechanistic studies suggest that transmetalation is rate-limiting. ...[more]