Transcriptomics

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Expression data from myocardial tissue from Spontaneously hypertensive rat (SHR) and its minimal congenic strain PD5


ABSTRACT: Spontaneously hypertensive rat (SHR; Rat Genome Database (RGD) ID: 631848) is probably the most commonly used rodent model for essential hypertension. Its minimal congenic subline PD5 ( SHR.PD-(D8Rat42-D8Arb23)/Cub; (RGD ID: 1641851)) which differs by a short segment of chromosome 8 (encompassing only 7 genes) displays lower levels of blood pressure and amelioration of cardiac fibrosis compared to SHR. We used microarray aproach to unravel gene expression differences between SHR and PD5 responsible for the different phenotypes in our rat strains.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE126709 | GEO | 2019/02/20

REPOSITORIES: GEO

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