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Influence of Dnmt3a knockout on gene expression of preleukemia B cell and CLL cells

ABSTRACT: Although somatic mutations in the DNA methyltransferase 3A (DNMT3A) in chronic lymphocytic leukemia (CLL) are rare, DNMT3A transcript and protein expression is frequently reduced in CLL patients, and previous studies have associated low DNMT3A expression with more aggressive disease and poorer survival.

ORGANISM(S): Mus musculus

PROVIDER: GSE169245 | GEO | 2021/10/01

REPOSITORIES: GEO

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