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RNA sequencing of control, DNMT1 knockout and DNMT1/L1TD1 double knockout haploid cells (HAP1)

ABSTRACT: To investigate the effects of L1TD1 ablation in DNMT1 knockout HAP-1 cells in comparison to DNMT1 knockout and control HAP1 cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE169614 | GEO | 2024/12/25

REPOSITORIES: GEO

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Identification of L1TD1-associated transcripts in DNMT1 KO HAP1 cells

Project description:In this study, we aimed at determining RNA interactors of L1TD1 RNPs. To achieve this, DNMT1 KO and DNMT1 L1TD1 DKO HAP1 cells were generated by Crispr/Cas9 gene editing tool and L1TD1 RIP was performed by using these cell lines. Our study reveals a comprehensive analysis of differentially enriched transcripts in L1TD1 containing RNPs.

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RNA sequencing of control, DNMT1 knockout and DNMT1/L1TD1 double knockout haploid cells (HAP1)

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