Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mettl3 regulates late-stage retinogenesis and mouse retina m6A epitranscriptome

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Mus musculus

PROVIDER: GSE180815 | GEO | 2022/12/02

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Mettl3 regulates late-stage retinogenesis and mouse retina m6A epitranscriptome

Project description:Mettl3 regulates late-stage retinogenesis and mouse retina m6A epitranscriptome

| PRJNA749616 | ENA

Mettl3 regulates late-stage retinogenesis

Project description:To study the function of Mettl3 during retinal development, we used Six3-Cre and Mettl3floxed mice to conditionally knock out Mettl3 from retinal progenitor cells. The mutant mice show defects in late-stage retinogenesis and structural and physiological homeostasis of the retina.

2022-12-03 | GSE180813 | GEO

Mettl3 regulates late-stage retinogenesis

Project description:Mettl3 regulates late-stage retinogenesis

| PRJNA749618 | ENA

Mettl3 regulates late retinogenesis

Project description:Mettl3 was conditionally knocked out from retinal progenitor cells. Metll3 deficient retinas exhibited disrupted cell cycle during late retinogenesis and abnormality in retinal architecture and physiology.

2022-12-02 | GSE181095 | GEO

Mettl3 regulates late retinogenesis

Project description:Mettl3 regulates late retinogenesis

| PRJNA750706 | ENA

Mouse retina m6A epitranscriptome

Project description:m6A epitranscriptome of postnatal day 6 mouse retina was sequenced using MeRIP-seq.

2022-12-03 | GSE180814 | GEO

Mouse retina m6A epitranscriptome

Project description:Mouse retina m6A epitranscriptome

| PRJNA749619 | ENA

neonatal and adult mouse retina m6A epitranscriptome [meRIP-seq]

Project description:m6A epitranscriptome of newborn and adult mouse retina was sequenced using MeRIP-seq

2022-12-02 | GSE188607 | GEO

m6A methyltransferase METTL3 regulates Tfh cell differentiation

Project description:This SuperSeries is composed of the SubSeries listed below.

2021-01-19 | GSE129650 | GEO

m6A readers, writers, erasers, and the m6A epitranscriptome in breast cancer.

Project description:Epitranscriptomic modification of RNA regulates human development, health, and disease. The true diversity of the transcriptome in breast cancer including chemical modification of transcribed RNA (epitranscriptomics) is not well understood due to limitations of technology and bioinformatic analysis. N-6-methyladenosine (m6A) is the most abundant epitranscriptomic modification of mRNA and regulates splicing, stability, translation, and intracellular localization of transcripts depending on m6A association with reader RNA-binding proteins. m6A methylation is catalyzed by the METTL3 complex and removed by specific m6A demethylase ALKBH5, with the role of FTO as an 'eraser' uncertain. In this review, we provide an overview of epitranscriptomics related to mRNA and focus on m6A in mRNA and its detection. We summarize current knowledge on altered levels of writers, readers, and erasers of m6A and their roles in breast cancer and their association with prognosis. We summarize studies identifying m6A peaks and sites in genes in breast cancer cells.

| S-EPMC9790079 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data